I am a theoretical chemist interested in computational biology and bioinformatics. I'm affiliated with the Research Group Bioinformatics and Computational Biology and the Theoretical Biochemistry group (TBI) at the Department of Theoretical Chemistry, University of Vienna. Our institute is known for the ViennaRNA Package.
About Michael Thomas Wolfinger
My research covers different aspects of algorithmic RNA bioinformatics, involving:
- Prediction of RNA secondary structures
- RNA folding dynamics and (re-)folding pathways
- In silico design of riboswitches for synthetic RNA biology
- RNA regulation in bacteria, archaea, and viruses
- Comparative genomics and virus evolution
- Discrete energy landscapes of biopolymers
- Equilibrium and non-equilibrium properties of complex disordered systems
- Efficient sampling strategies
I collaborate with biologists and clinical scientists in next-generation sequencing (NGS) projects, thereby developing software tools like ViennaNGS, a collection of Perl Modules for NGS analysis. Being passionate about Linux, open source software and Web standards, I love to code in C and Perl6.
Alongside my day job as a research scientist, I give lectures in algorithmic bioinformatics and Web Services at the Vienna University of Applied Sciences.